Carbetocin si looga hortago xanuunka uterine
Si faahfaafo
| Magac | Carbetocin |
| Lambarka CAS | 37025-55-1 |
| Qaaciddada molika | C45h69n11o12s |
| Miisaanka Moleculal | 988.17 |
| Tirada EINECS | 253-312-6 |
| Wareejin gaar ah | D -69.0 ° (c = 0.25 ee 1m acetic acid) |
| Point karkaraya | 1477.9 ± 65.0 ° C (saadaaliyay) |
| Cucid | 1.218 ± 0.06 g / cm3 (la saadaaliyay) |
| Xaaladaha kaydinta | -15 ° C |
| Qaab | budo |
Ereyo isku mid ah
BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2, (SULFIDEBONDBETWEENBUTYRYL-4-YLANDCYS); Butyryl-Tyr (aniga) (aniga) -ile-gln-asn-cys-pro-leu-gly-gly-nh2tluoroooroacetates; (Butyryl1, Tyr (aniga (i) 2) -1-Carbaoxytoc Intifluorooroct; (Butyryl1, Tyr (i) 2) -Oxytocin; (Butyryl1, Tyr (aniga (i) 2) -oxytoctrifluoretatetates; Carbetocin; CarbetoCindintluetacateteracetacetatetates; (2-o-metyltyrintosine) -de-amino-1-carbahooytocin
Waxqabadka bayoolojiga
Carbetocin, oo ah oxyyocin (OT) Analog, waa soo-saare oxytocin, Agritor Agritor oo leh KIe of 7.1 NM. Carbetocin waxay leedahay xiriir sare (ki = 1.17 μm) oo loogu talagalay chimerinis n-erimus ee oxytocin-ka oxyyocin. Carbetocin waxay leedahay awood u leh cilmi baarista dhiigbaxa ee dhalmada ka dib. Carbetocin-ka wuxuu dhex geli karaa xannibaadda maskaxda-maskaxda wuxuuna ku dhacaa fal ka hortag-likes-u eg isagoo ku dhaqaaqaya soo-dhoweynta oxytocin ee CNS-yada.
Shaqayn
Carbetocin waa mid isku-dhafan oo ah oxythos-ka-caadiga ah ee ''-PetDocin ' Sida oxytocin, Carbetotion-ka oo ay ku xidhaan hoormoonka hoormoonka muruqa mishiinka jilicsan, taasoo keenaysa foosha laxanka ee ilmo galeenka, kordhinta soo noqnoqda ee ku saleysan codka mawjada ee asalka ah. Heerarka oxyttocin ee heeganka ilmo galeenka ayaa ku hooseeya gobolka aan uurka lahayn, kordhi inta lagu jiro uurka, iyo ugu sarreeya inta lagu jiro foosha. Sidaa daraadeed, Carbetocin wax saameyn ah kuma lahan uterus-ka aan uurka lahayn, laakiin waxay saameyn ku leedahay qandaraas gacmeed xasaasiyad leh ilmo galeenka uurka leh iyo makaanka dhowaan la soo saaray.
Beddel kontaroolada
Isbedelada waxaa lagu xakameeyaa nidaamka. Iyada oo ku saleysan saameynta iyo halista iyo darnaanta, isbeddelada waxaa loo kala saaraa inay yihiin wax weyn, yar iyo goobta. Isbedelada goobta ayaa saameyn yar ku leh badbaadada iyo tayada badeecada, sidaa darteedna uma baahna oggolaansho iyo ogeysiin macaamiisha; Isbeddellada yar yar waxay leeyihiin saameyn dhexdhexaad ah oo ku saabsan badbaadada iyo tayada wax soo saarka, waxayna u baahan yihiin in la ogeysiiyo macaamiisha; Isbeddellada waaweyn waxay leeyihiin saameyn sare oo ku saabsan badbaadada iyo tayada wax soo saarka, waxayna u baahan tahay ansixin macmiilka.
Marka loo eego habraaca, xakamaynta isbedelka ayaa lagu bilaabay isbedelka arjiga isbedelka kaas oo faahfaahinta isbeddelka iyo macquulka ah ee isbedelka lagu sharaxay. Qiimaynta ayaa markaa la sameeyaa kadib dalabka, kaas oo lagu sameeyo waaxyada ku habboon ee xakamaynta isbedelka. Dhanka kale, xakamaynta isbedelka ayaa loo kala saaraa heer weyn, heerka guud iyo heerka yar. Kadib qiimeynta ku habboon iyo sidoo kale kala-soocidda, dhammaan xakamaynta isbedelka heerka waa in ay ansixiyaan maamulaha QA. Xakamaynta isbedelka ayaa la fuliyaa ka dib oggolaanshaha iyadoo la raacayo qorshaha waxqabadka. Xakamaynta isbedelka ayaa ugu dambeyntii xiran kadib markii QA uu xaqiijiyo kontaroolka isbedelka si munaasib ah loo hirgaliyay. Haddii ay ku lug yeelato ogeysiinta macmiilka, macmiilka waa in la ogeysiiyaa waqtigii ku habboon ka dib markii la ansixiyay xakamaynta isbedelka
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