Atosiban Acetate Used for Anti Premature Birth Featured Image

Atosiban Acetate Loo Isticmaalay Dhalashada Ka Hortagga Ah

Sharaxaad Gaaban:

Magaca: Atosiban

Lambarka CAS: 90779-69-4

Qaaciddada molecular: C43H67N11O12S2

Miisaanka molecular: 994.19

Lambarka EINECS: 806-815-5

Barta karkarinta: 1469.0± 65.0 °C (La saadaaliyay)

Cufnaanta: 1.254±0.06 g/cm3(La saadaaliyay)

Xaaladaha kaydinta: -20°C

Solubility: H2O: ≤100 mg/ml

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Faahfaahinta Alaabta

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Faahfaahinta Alaabta

Magaca	Atosiban
Lambarka CAS	90779-69-4
qaacidada molecular	C43H67N11O12S2
Miisaanka molecular	994.19
Lambarka EINECS	806-815-5
Barta karkarinta	1469.0± 65.0 °C (La saadaaliyay)
Cufnaanta	1.254±0.06 g/cm3 (La saadaaliyay)
Xaaladaha kaydinta	-20°C
Solubility	H2O: ≤100 mg/ml

Sharaxaada

Atosiban acetate waa polypeptide wareeg ah oo disulfide ku xidhan oo ka kooban 9 amino acids.Waa molecule oxytocin oo la bedelay ee boosaska 1, 2, 4 iyo 8. N-terminus ee peptide waa 3-mercaptopropionic acid (thiol iyo Kooxda sulfhydryl ee [Cys] 6 waxay sameeyaan bond disulfide ah), C-terminal waa qaabka amide, amino acid labaad ee N-terminal waa ethylated modified [D-Tyr (Et)]2, iyo atesiban acetate waxaa loo isticmaalaa daawooyinka sida khal Waxay u jirtaa qaabka cusbada acid, caadi ahaan loo yaqaan atosiban acetate.

Codsiga

Atosiban waa oxytocin iyo vasopressin V1A isku-dhafan oo ka soo horjeeda soo-dhoweeyaha, oxytocin reseptor wuxuu qaab ahaan la mid yahay xajiyaha vasopressin V1A.Marka la xannibo soo-dhoweynta oxytocin, oxytocin wali waxay ku dhaqmi kartaa iyada oo loo marayo soo-dhoweynta V1A, sidaas darteed waa lagama maarmaan in la xannibo labada dariiq ee kor ku xusan isla mar, iyo hal lid ku ah hal reseptor ayaa si wax ku ool ah u joojin kara foosha ilmo-galeenka.Tani sidoo kale waa mid ka mid ah sababaha ugu muhiimsan ee agonists β-receptor, kaalshiyamka kanaalka kaalshiyamka iyo prostaglandin synthase inhibitors aysan si wax ku ool ah u joojin karin foosha ilmo-galeenka.

Saamaynta

Atosiban waa antagonist isku dhafan oo ah oxytocin iyo vasopressin V1A, qaab dhismeedkeeda kiimikaad waxay la mid tahay labada, waxayna leedahay xiriir sare oo loogu talagalay reseptors, waxayna la tartantaa oxytocin iyo vasopressin V1A, taas oo xannibaysa dariiqa ficil ee oxytocin iyo vasopressin waxayna yareysaa foosha ilmagaleenka.

Hore: Teriparatide Acetate API ee Lafo-jileeca CAS NO.52232-67-4

Xiga: Carbetocin si ay uga hortagto foosha Uterine-ka iyo Dhiig-baxa dhalmada ka dib

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