Ste-γ-Glu-AEEA-AEEA-OSU

Ste-γ-Glu-AEEA-AEEA-OSU

Ste-γ-Glu-AEEA-AEEA-OSU waa unug isku xidhaha dufan leh ee synthetic oo loogu talagalay gaarsiinta daroogada la beegsaday iyo isku-xidhayaasha-daawooyinka-ka-hortagga (ADCs). Waxay ka kooban tahay dabada stearoyl (Ste) hydrophobic, γ-glutamyl ujeedka bartilmaameedka ah, AEEA spacers ee dabacsanaanta, iyo kooxda OSU (NHS ester) ee isku xidhka hufan.

 
Cilmi-baarista & Codsiyada:

Waxaa loo adeegsaday isku-darka dawada la beegsaday iyo naqshadeynta nanocarrier

Waxay xoojisaa isdhexgalka xuubabka unugga iyo qaadashada daroogada

Waxay fududaysaa ku xidhidhiyaha lacag bixinta ee gaarka ah ee peptides, unugyada difaaca jirka, ama sidayaal

Astaamaha Alaabta (Kooxda Gentolex):

Nadiifin sarreeya, diyaar u ah in la isku xidho NHS ester

Ku habboon bioconjugation iyo cilmi-baarista gaarsiinta la beegsaday

Ste-γ-Glu-AEEA-AEEA-OSU waxay ku habboon tahay horumarinta nidaamka bixinta daroogada saxda ah.