Sembulutide nooca 2 ee sonkorowga

Semiglutide waa jiil cusub oo ah glp-1 (glucagon-sida peptide-1) analogs, oo ah qaab qaadasho qiyaaseed oo muddo dheer ah, oo saameyn wanaagsan ku leh daaweynta sonkorowga Nooca 2 ah. Shirkadda Novo Nordisk ayaa dhameystirtay 6 waji Iiiya Daraasadii Cirbadaha Sembutide-ka ee 'Sembutide' oo loogu tala galay in laga gaaro Maamulka Cuntada ee Sembuteide (FDA).

Marka la barbar dhigo lilaglutide, sembutide, semiglutide waxay leedahay silsilad xasaasi ah oo dheeri ah oo kordhaysa hydrophobicity, laakiin sembluticity waxaa lagu beddelaa silsilad gaagaaban oo biyuhu si weyn u wanaajiyaan. Ka dib dib-u-habeynta PEG ka dib, kuma xirna oo keliya goobta 'endrolysis' ee 'endrolysis' ee dp-4, laakiin waxay sidoo kale yareysaa tax-reebitaanka noolaha, oo sii dheeraato nolosha noolaha, oo ay ku guuleystaan ​​saamaynta wareegga dheer.