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L-carnitine waa in laga caawiyo qaadista qaadista acids-ka mudada dheer ee tamarta tamarta

Sharraxaadda Gaaban:

Bartirka dhalaalaya: 197-212 ° C (iftiin)

Wareejin gaar ah: -31º (c = 10, H2O)

Point Point: 287.5 ° C (qiyaasta adag)

Cufnaanta: 0.64g / cm3

Tusmada Fikradda ah: -32 ° (c = 1, H2O)

Shuruudaha kaydinta: Batirew + 30 ° C.

SOLUBENES: H2O: 0.1g / kiimikada

Foom: CrystastorcySTinderpownder

Canshtity Coffient: (PKA) 3.80 (AT25 ℃)

Midab: Caddaan

PH qiimaha: 6.5-8.5 (50g / L, H2O)

Xoolaha biyaha: 2500g / l (20ºC)


Si faahfaafo

Calaamadaha wax soo saarka

Si faahfaafo

Magac L-carnitine
Lambarka CAS 541-15-1
Qaaciddada molika C7h15no3
Miisaanka Moleculal 161.2
Dhibcaha dhalaalaya 197-212 ° C
Point karkaraya 287.5 ° C
Daahir 99%
Bakhaar Kaydso hoosta + 30 ° C
Qaab Budo
Midab Cad
Isku xiris PE bac + bacda aluminium

Ereyo isku mid ah

Carnitine, L-; Carninfedeed (R); Carniking (R); Car -F-oh; Me3-Gameta-Abuu;-Beta-hydroxy-gamma- gamma- (trimethylymamy) Qiimaha;

Saamaynta dawooyinka

Shaqada jir ahaaneed iyo door

L-carnitine sidoo kale waxay leedahay saameyn gaar ah oo kor loogu qaadayo ka-faa'iideysiga jirka ee ketone ah iyo dheef-shiid kiimikaadka nitrogen.

1. Dhiirrigelinta gaadiidka iyo oksidation of acids dufanka leh ee β-oxxation of dufanka aashitada dufanka leh waxaa lagu sameeyaa mitochondria ee beerka iyo unugyada kale ee unugyada. Waxaa la ogsoon yahay in acids-ka dufanka aan lahayn ama dufanka aan lahayn midkoodna uusan dhex gelin karin xuubka mitochondrial, laakiin asycharnitine wuxuu si dhakhso leh u gudbin karaa aashitada dufanka ah ee xuubka dufanka leh ee loo yaqaan 'mitochondrondriint' oo ah nooc ka baxsan xuubka. Qaabka faahfaahsan ee gaadiidkan ma cadda, laakiin waa hubaal in Cartineacyleacees-goatineacyl-Gunitineacyl-GueronsanyFese) ay tahay EnzyFese) waa Enzyfe-ka ee hawshan. Dadka qaarkiis waxay moodayaan in L-carnitine ay sidoo kale ka qeybqaadan karto gaadiidka iyo kooxaha kale ee askyl, sidaa darteed waxay ka hortegi kartaa jirka in uu ku sumoobo dheef-shiid kiimikaadka ama u sahli karo dheef-shiid kiimikaadka caadiga ah ee acids amino-amino-amino-amino.

2. Dardar-gelinta koriinka shahwada iyo hagaajinta muhiimadda leh l-carnitine waa walax tamar ah oo loogu talagalay koriinka shahwada, kaas oo leh howsha tirinta shahwada iyo muhiimadda. Sahaminta 30 ragga oo waaweyn waxay muujineysaa in tirada iyo muhiimadda shahwada ay si toos ah u dhigan tahay sahayda L-carnitine ee cuntada gudaheeda, oo ka kooban shahwada sidoo kale waxay si togan ku xiran tahay nuxurka L-carnitine ee cuntada.

3. Hagaajinta dulqaadka jidhka ee jirka et al. Waxaa lagu ogaaday in L-carnitine ay hagaajin karto dulqaadka bukaanka qaba cudurada inta lagu gudajiro jimicsiga, sida waqtiga jimicsiga, oksijiyada ugu badan ee oksijiinka, kabitaannada jirka ee oksijiinta ah, kabitaannada jirka ee oksijiinta ah, ka dib, waxaa jiri doona heerar kala duwan oo horumar ah; Afka L-carnitine wuxuu kaloo kordhin karaa dulqaad muruqyada waqtiga ugu badan ee oksijiinta ugu badnaan ee 80%, gaabiso muddada soo kabashada ka dib jimicsi culus, oo uu yareeyo xiisadda iyo daalka ay sababaan jimicsi. Santulli et al. Waxaa la helay sanadkii 1986 in L-carnitine ay kordhin karto heerka koritaanka ee jabsiga oo loo yareeyo waxa ku jira kolestaroolka iyo triglyceride ee unugyada kalluunka. Jarmalka ayaa sheegay in ka dib markii uu qaatay L-carnitine muddo 3 todobaad ah, waxa ku jira dufanka jirka ee ciyaartooyda si weyn hoos ugu dhacday, laakiin saamiga borotiinka ayaa kordhay, laakiin miisaanka jirka ma saameynin.


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