Eptifibatide loogu talagalay daawaynta xanuunka wadnaha ee ba'an 188627-80-7
Faahfaahinta Alaabta
| Magaca | Eptifibatide |
| Lambarka CAS | 188627-80-7 |
| qaacidada molecular | C35H49N11O9S2 |
| Miisaanka molecular | 831.96 |
| Lambarka EINECS | 641-366-7 |
| Cufnaanta | 1.60±0.1 g/cm3 (La saadaaliyay) |
| Xaaladaha kaydinta | Ku dabool qallalan, ku kaydi qaboojiyaha, ka hooseeya -15 ° C |
La mid ah
Eptifibatideacetatesalt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2,>99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide; (Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2 (DISULFIDEBRIDGE,MPA1-CYS6).
Platelet Glycoprotein antagonist
Etifibatide (integrilin) waa sheeko cusub oo ah polypeptide platelet glycoprotein IIb/IIIa antagonist receptor antagonist, kaas oo joojiya isku-darka platelet iyo thrombosis iyadoo la joojinayo dariiqa ugu dambeeya ee isku dhafka platelet.Marka la barbar dhigo monoclonal antibody abciximab, eptifibatide waxay leedahay mid ka xoog badan, jiho badan oo gaar ah oo ku xidhan GPIIb/IIIa sababtoo ah jiritaanka hal muxaafid amino acid beddel ah—lysine si loogu beddelo arginine.Sidaa darteed, waa inay lahaataa saameyn wanaagsan oo daaweyn ah oo ku saabsan daaweynta faragelinta ee xanuunka wadnaha ee degdega ah.Platelet glycoprotein IIb/IIIa receptor antagonist daawooyinka aad ayaa loo sameeyay, waxaana hadda jira 3 nooc oo diyaargarow ah oo loo isticmaali karo kiliinikada caalamiga ah, abciximab, eptifibatide iyo tirofiban.).Waxaa jira khibrad yar oo ku saabsan isticmaalka platelet glycoprotein GPIIb/IIIa antagonists ee Shiinaha, iyo daawooyinka la heli karo sidoo kale aad bay u xaddidan yihiin.Hal daawo, tirofiban hydrochloride, ayaa suuqa taal.Sidaa darteed, platelet glycoprotein IIb cusub ayaa la sameeyay./IIIa receptor antagonists waa lama huraan.Eptifibatide gudaha waa badeecad ku dayasho ah oo ay soo saartay Chengdu Sino Biological Products Co., Ltd.
Kala soocidda
Kala-soocidda Dawooyinka Isku-darka Antiplatelet
Daawooyinka isku-darka ah ee antiplatelet waxa loo qaybin karaa qiyaas ahaan saddex qaybood: 1. Cyclooxygenase-1 (COX-1) inhibitors, sida aspirin.2. Jooji isku-darka platelet-ka oo ay keento adenosine diphosphate (ADP), sida clopidogrel, prasugrel, cangrelor, ticagrelor, iwm. prostaglandin EP3 receptor inhibitors, qaybo kiimiko ah oo dhawaan la soo saaray iyo wax soo saar wax ku ool ah oo laga soo qaatay daawada dhaqameed ee Shiinaha.
