Eptifibatide loogu talagalay daawaynta xanuunka wadnaha ee ba'an 188627-80-7
Faahfaahinta Alaabta
| Magaca | Eptifibatide |
| Lambarka CAS | 188627-80-7 |
| qaacidada molecular | C35H49N11O9S2 |
| Miisaanka molecular | 831.96 |
| Lambarka EINECS | 641-366-7 |
| Cufnaanta | 1.60±0.1 g/cm3 (La saadaaliyay) |
| Xaaladaha kaydinta | Ku dabool qallalan, ku kaydi qaboojiyaha, ka hooseeya -15 ° C |
La mid ah
Eptifibatideacetatesalt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2,>99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide(Amin); nomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2(DISULFIDEBRIDGE,MPA1-CYS6).
Platelet Glycoprotein antagonist
Etifibatide (integrilin) waa sheeko cusub oo ah polypeptide platelet glycoprotein IIb/IIIa antagonist receptor antagonist, kaas oo joojiya isku-darka platelet iyo thrombosis iyadoo la joojinayo dariiqa ugu dambeeya ee isku dhafka platelet. Marka la barbar dhigo monoclonal antibody abciximab, eptifibatide waxay leedahay mid ka xoog badan, jiho badan oo gaar ah oo ku xidhan GPIIb/IIIa sababtoo ah jiritaanka hal muxaafid ah oo amino acid ah -lysine si ay u badasho arginine. Sidaa darteed, waa inay lahaataa saameyn daweyn oo wanaagsan oo ku saabsan daaweynta faragelinta ee xanuunka wadnaha ee degdega ah. Platelet glycoprotein IIb/IIIa receptor antagonist daawooyinka aad ayaa loo sameeyay, waxaana hadda jira 3 nooc oo diyaargarow ah oo loo isticmaali karo kiliinikada caalamiga ah, abciximab, eptifibatide iyo tirofiban. ). Waxaa jira khibrad yar oo ku saabsan isticmaalka platelet glycoprotein GPIIb/IIIa antagonists ee Shiinaha, iyo daawooyinka la heli karo sidoo kale aad bay u xaddidan yihiin. Hal daawo, tirofiban hydrochloride, ayaa suuqa taal. Sidaa darteed, glycoprotein IIb platelet cusub ayaa la sameeyay. /IIIa receptor antagonists waa lama huraan. Eptifibatide gudaha waa badeecad ku dayasho ah oo ay soo saartay Chengdu Sino Biological Products Co., Ltd.
Kala soocidda
Kala-soocidda Dawooyinka Isku-darka Antiplatelet
Dawooyinka isku-darka ah ee Antiplatelet waxa loo qaybin karaa qiyaas ahaan saddex qaybood: 1. Cyclooxygenase-1 (COX-1) inhibitors, sida aspirin. 2. Jooji isku-darka platelet-ka ee ay keento adenosine diphosphate (ADP), sida clopidogrel, prasugrel, cangrelor, ticagrelor, iwm. Qayb cusub oo kiimiko ah oo la farsameeyey iyo wax-soosaar waxtar leh oo laga helay dawo-dhaqameedka Shiinaha.
