Desmopressin Acetate si loo daaweeyo Insipidus-ka-macaanka dhexe
Faahfaahinta Alaabta
| Magaca | Desmopressin |
| Lambarka CAS | 16679-58-6 |
| qaacidada molecular | C46H64N14O12S2 |
| Miisaanka molecular | 1069.22 |
| Lambarka EINECS | 240-726-7 |
| Wareegid gaar ah | D25 +85.5 ± 2° (waxaa lagu xisaabiyay peptide-ka bilaashka ah) |
| Cufnaanta | 1.56±0.1 g/cm3 (La saadaaliyay) |
| RTECS Maya. | YW9000000 |
| Xaaladaha kaydinta | Ku kaydi heerkulka 0°C |
| Solubility | H2O: milmay20mg/ml, cad, aan midab lahayn |
| Isku-dhafka aysiidhka | (pKa) 9.90±0.15 (La saadaaliyay) |
La mid ah
MPR-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2; MINIRIN; [DEAMINO1, DARG8] VASOPRESSIN; [DEAMINO-CYS1, D-ARG8] -VasoPRESSIN; DDAVP, AADANAHA; DESMOPRESSIN; DESMOPRESSIN, AADAN; DESAMINO-[D-ARG8] VASOPRESSIN
Tilmaamaha
(1) Daaweynta sonkorowga dhexe insipidus. Ka dib daawadu waxay yareyn kartaa qashinka kaadida, waxay yareysaa inta jeer ee kaadida waxayna yareyneysaa nocturia.
(2) Daaweynta nocturnal enuresis (bukaanada da'doodu tahay 5 sano ama ka weyn).
(3) Tijaabi hawsha fiirsashada kaadida kelyaha, oo samee ogaanshaha kala duwanaanshaha shaqada kelyaha.
(4) Hemophilia iyo cudurrada kale ee dhiigbaxa, badeecadani waxay soo gaabin kartaa wakhtiga dhiigbaxa waxayna ka hortagi kartaa dhiigbaxa. Waxay yarayn kartaa qadarka luminta dhiigga qalliinka iyo qulqulka qalliinka ka dib; gaar ahaan iyadoo lala kaashanayo cadaadiska dhiigga oo si macquul ah loo kontoroolo xilliga qalliinka, waxay yareyn kartaa dhiigbaxa qalliinka ee ka imaanaya habab kala duwan, waxayna yareyn kartaa qulqulka qalliinka kadib, taas oo door wanaagsan ka qaadan karta ilaalinta dhiigga.
Daawaynta xanuunka macaanka insipidus
Sonkorowga insipidus waa khalkhal ku yimaada dheef-shiid kiimikaadka biyaha oo lagu garto soo saarista kaadida xad-dhaafka ah, polydipsia, hypoosmolarity, iyo hypernatremia. La'aanta qayb ahaan ama dhamaystiran ee vasopressin (insipidus sokorowga dhexe), ama kelyaha oo yaraada vasopressin (nephrogenic diabetes insipidus) ayaa bilaaban kara. Kiliinik ahaan, insipidus-ka macaanku waxa uu la mid yahay polydipsia aasaasiga ah, xaalad ah in qaadashada dareeraha xad-dhaafka ah ay sababto cillad hab-socodka nidaaminta ama harraad aan caadi ahayn. Si ka soo horjeeda polydipsia aasaasiga ah, korodhka qaadashada biyaha ee bukaanada qaba xanuunka macaanka insipidus waa jawaab celin u dhiganta isbeddelada cadaadiska osmotic ama mugga dhiigga.
