Sedenafil citrate Dawlaynta qalalaase ee Ecyfunfle 171599-83-0 Sawirka Muuqaalka

Seldenafil citrate Dawlaynta qalalaase Checfunctile dysfunction 171599-83

Sharraxaadda Gaaban:

Qaaciddada kiimikada: c28h38n6o11s

Miisaanka Moleculal: 666.70

Lambarka CAS: 171599-83-0

Tirada EINECS: 200-659-6

Barta dhalaalaysa: 187-189 ℃

Point Point: 672.4 ℃

Barta Flash: 360.5 ℃

Cufnaanta: 1.445g / cm3

Tusmada firfircoonaanta: 1.683

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Si faahfaafo

Magac	Seldenafil citrate
Lambarka CAS	171599-83-0
Qaaciddada molika	C28H38NN6SE11S
Miisaanka Moleculal	666.70
Tirada EINECS	200-659-6
Merck	14,8489
Cucid	1.445g / cm3
Xaaladda kaydinta	2-8 ° C
Qaab	Budo
Midab	Cad
Xarkaha biyaha	Dmso:> 20mg / ml

Ereyo isku mid ah

Viagra, Seldenafil Citerate; 1 - [3- (4,7-DIHYDDRO-1-Methyl-1-oxo-3-pypyl-1h-pyrozolo [4-yl) -4-Ethoxylphenyl] -4-Ethoxylpiperperazintrateteratet; 5- [2-Etheroxy-5- (4-Methylpiperazin-1-yl) Sulfodonlepryl] -1-'methylpronlepryl] -1-linylpon-3-linyl-3-eyl-pyrazolo [5,4-ecylplo " 1 - [3,7-DIHYDDRO-1-Methyly-1-oxo-3-pypyl-1h-pyrazolo [4-ethoxylpiperazine] -4-ethoxypypiperazine, 2-hydroxy-1,2,3-propanetriparxuulate; Sedenabcilcitcitritt (100mg); Sedenabcilcilcitcitrit,> = 99%; Seldelafaflift, xirfadlayaal; 5- [2-Etyfoxy-5 - [4-methyl-piperazin-1-yl) Sulfinl] -1-YL) Phenyl] -1-dihydro-1-linyly-7-pyrazolo [4,3-drydylo [4,3-d] pyrimidirin-7-dry.

Saamaynta dawooyinka

Ficilka dawooyinka
Seldenafil Citirate waa 5-fosfooris-xumo Ka sokow ballaarinta tooska ah ee xididdada dhiigga ee sambabka, waxay sidoo kale ka hortegi kartaa ama dib uga noqon kartaa hagaajinta xididdada xididdada.

Guryaha Dawooyinka iyo Codsiyada
Saldenafil Citterate, Magaca ganacsiga Viagre, oo caadi ahaan loo yaqaan vianosine-ka is-afgambiyada (cgmp) -Spececific fosphodphiereserase Nooca 5 (PDE5) ee kor u qaadida ka dib maamulka afka. Seldenafil citrate wuxuu kor u qaadayaa saameynta nitric oxide (Maya) iyadoo la xakameynayo nooca 5 phosphist Guanosine-ka 'Cirmpic Gunosine' (cgmp) ee corpus caverosem. Kordhi heerka CGMP ee Corpus Caventosum, oo ku naso muruqyada jilicsan ee Corpus Caventosum, oo kor u qaad dhiiga dhiigga, dheereynta waqtiga kacsiga oo kor u qaadaya. BAADHITAANKA ISTICMAALKA BAARITAANKA CARRUURTA EE DHAQANKA. Dadka waaweyni waxay qaataan 50 mg af ahaan wakhti kasta, illaa 1 jeer maalintii, oo u isticmaal sidii loogu baahnaa 1 saac kahor galmada. Lacagta ugu badan waa 0.1g waqti kasta.

Daraasadaha vivo
Eeyaha suuxinta, Seldenafil Citterate waxay ku sii wadaysaa howlo qalad ah oo ka hooseysa dhaqdhaqaaqa miskaha dareeraha miskaha ee lagu cabiro cadaadis-dhimis. Seldenafil Cititerately si muuqata u noqotay nasashada oo curyaamisay carbamoyllholine-kicinta carbamoolinl-kicinta ah oo la xakameeyay qaab-dhismeedka supernotic-ka ee cawska camafka ah ee bakaylaha guryaha. Jiirka Sprague-Dawnley, Seldenafil waxay soo hagaageysaa shaqada elecilada hab waqti-qaadasho ah, oo leh soo-kabasho guud oo ka dhacaya maalinta 28 ee qiyaasta 20 mg / kg maalintii. Jiirka Sprague-Dawley, oo maamulka Sedennafil ayaa dhaliyay in ay ka dhasheen ilaalinta murqaha ee jilicsan iyo dhawrista CD31 iyo muujinta Enoos. Jiirka SPRAGAE-Dawley, Seldenafil ayaa si weyn hoos ugu dhigay tusaha apoptotic waxayna kordhisay phosprorypring of akt iyo enoos marka la barbar dhigo kooxda kantaroolka.

Hore: Tadialafil 171596-29-5 si loo daweeyo ciribtirka qaladka ee ragga

Xiga: Vardenafil DIHYDDOCHOORLIIDE DECTENDFILE CHYSFENFUNENT 22785-91-5

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