Alaabta
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CJC-1295
CJC-1295 API waxaa la soo saaray iyadoo la adeegsanayo tignoolajiyada adag ee peptide synthesis (SPPS) waxaana lagu nadiifiyaa iyadoo la isticmaalayo HPLC si loo gaaro nadiifnimo sare iyo joogteynta Dufcaddii-ilaa- Dufcaddii.
Astaamaha Alaabta:daahirnimo ≥ 99%
Walxaha haraaga ah ee hooseeya iyo biraha culus
Endotoxin-free, waddada isku-dhafka aan difaaca jirka ahayn
Tirada la beddeli karo: mg ilaa kg
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NAD+
Tilmaamaha API:
Nadiifin sare ≥99%
NAD+-dawada
Heerarka wax soo saarka ee GMP
NAD+ API waxay ku habboon tahay in loo isticmaalo nafaqooyinka, cirbadaha, iyo daawaynta dheef-shiid kiimikaad sare leh.
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Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OHwaa tetrapeptide la ilaaliyo oo caadi ahaan loo isticmaalo cilmi baarista isku dhafka peptide. Kooxaha Boc (tert-butyloxycarbonyl) iyo tBu (tert-butyl) waxay u adeegaan sidii kooxo ilaalin ah si ay uga hortagaan falcelinta dhinaca inta lagu guda jiro isu imaatinka silsiladda peptide. Ku darida Aib (α-aminoisobutyric acid) waxay gacan ka geysataa soo saarista qaababka helical iyo kordhinta xasilloonida peptide. Isku xigxiga peptide-kan waxaa lagu daraaseeyaa kartida uu u leeyahay falanqaynta qaabaysan, laalaabida peptide, iyo sidii dhisme dhisme loogu horumarinayo peptides bioactive oo leh xasillooni iyo gaar ahaaneed.
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Cagrilintide
Cagrilintide waa synthetic, amylin reseptor agonist oo muddo dheer shaqaynaysa oo loo sameeyay daaweynta buurnaanta iyo xanuunnada dheef-shiid kiimikaadka la xiriira. Iyagoo ku dayanaya hormoonka dabiiciga ah ee amylin, waxay ka caawisaa nidaaminta rabitaanka cuntada, hoos u dhigista faaruqinta caloosha, iyo kor u qaadida dheregnaanta. Cagrilintide API ee nadiifka ah ee nadiifka ah waxaa lagu soo saaraa isku-darka kiimikaad waxayna la kulantaa heerarka-farmasiga, taasoo ka dhigaysa mid ku habboon in loo isticmaalo hababka maaraynta miisaanka horumarsan.
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Tesamorelin
Tesamorelin API waxay isticmaashaa tignoolajiyada horumarsan ee adag ee peptide synthesis (SPPS) waxayna leedahay sifooyinka soo socda:
Nadiifinta ≥99% (HPLC)
Ma jiro endotoxin, biraha culus, dareerayaasha haraaga ah ee la tijaabiyay
Amino acid isku xigxiga iyo qaab dhismeedka uu xaqiijiyay LC-MS/NMR
Bixi wax soo saar la habeeyey oo garaam ilaa kiilo garaam -
Fmoc-Ile-Aib-OH
Fmoc-Ile-Aib-OH waa dhisme dipeptide ah oo loo isticmaalo isku-dhafka peptide-wajiga adag (SPPS). Waxay isku daraysaa isoleucine-ilaaliya Fmoc iyo Aib (α-aminoisobutyric acid), oo ah amino acid aan dabiici ahayn oo kor u qaadaya xasilloonida helix iyo iska caabbinta protease.
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![Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH](https://cdn.globalso.com/gentolexgroup/Glepaglutide6-300x300.png)
Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA] -OH waa dhisme amino acid shaqaynaysan oo loogu talagalay gaarsiinta daroogada la beegsaday iyo bioconjugation. Waxay ka kooban tahay Eic (eicosanoid) moiety isdhexgalka lipid, γ-Glu bartilmaameedka, iyo AEEA spacers ee dabacsanaanta.
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Boc-Tyr(tBu)-Aib-OH
Boc-Tyr(tBu)-Aib-OH waa dhisme dipeptide ah oo la ilaaliyo oo loo isticmaalo isku dhafka peptide, isku darka Boc-protected tyrosine iyo Aib (α-aminoisobutyric acid). Hadhaaga Aib waxa ay xoojisaa samaynta helix iyo iska caabbinta protease.
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Boc-His(Trt)-Ala-Glu(OtBu)-Gly-OH
Boc-His(Trt)-Ala-Glu(OtBu)-Gly-OH waa jajab tetrapeptide ah oo la ilaaliyo oo loo isticmaalo isku dhafka adag ee peptide synthesis (SPPS) iyo horumarinta daroogada peptide. Waxaa ka mid ah kooxaha difaaca ee isku-dhafka orthogonal waxayna soo bandhigaysaa taxane faa'iido u leh naqshadaynta bioactive iyo qaab dhismeedka peptide.
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Fmoc-Lys(Pal-Glu-OtBu)-OH
Fmoc-Lys(Pal-Glu-OtBu) -OH waa unug dhismeed amino acided gaar ah oo loogu talagalay isku xirka dufanka-peptide. Waxay ka kooban tahay lysine-ka ilaalisa Fmoc oo leh silsilad dhinaca palmitoyl-glutamate, taasoo kor u qaadaysa xidhiidhka xuubka iyo noolaha.
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Fmoc-His-Aib-OH
Fmoc-His-Aib-OH waa dhisme dipeptide ah oo loo isticmaalo isku-dhafka peptide, isku darka Fmoc-la ilaaliyo histidine iyo Aib (α-aminoisobutyric acid). Aib waxay soo bandhigaysaa qallafsanaan, taasoo ka dhigaysa mid qiimo leh naqshadaynta helical iyo peptides deggan.
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Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH waa jajab tetrapeptide ah oo la ilaaliyo oo loo isticmaalo isku dhafka peptide iyo horumarinta daroogada. Waxay ka kooban tahay kooxo hawleed si istiraatijiyadeed loo ilaaliyo oo loogu talagalay isku dhafka jaranjarada iyo sifooyinka Aib (α-aminoisobutyric acid) si kor loogu qaado xasilloonida helix iyo qallafsanaanta qaabaysan.