Peptide APIs
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Tirzepatide
Tirzepatide waa laba-geesood cusub oo GIP iyo GLP-1, oo loo sameeyay daawaynta nooca 2 ee sonkorowga iyo buurnaanta. Sida fasalka koowaad ee "twincretin," Tirzepatide waxay wanaajisaa dheecaanka insulin, waxay xakameysaa sii deynta glucagon, waxayna si weyn u yareysaa rabitaanka cuntada iyo miisaanka jirka. Tirzepatide API ee nadiifinta-sare ah waa mid kiimiko ahaan la soo saaray, oo xor ka ah wasakhaha ka soo jeeda unugga martida loo yahay, oo la kulma heerarka sharci ee caalamiga ah ee tayada, xasilloonida, iyo miisaanka.
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Semaglutide
Semaglutide waa GLP-1 daaweeyaha receptor agonist oo muddo dheer shaqeynaya oo loo isticmaalo daaweynta nooca 2aad ee sonkorowga iyo maareynta miisaanka daba dheeraada. Semaglutide API ee nadiifka ah ee nadiifka ah waxaa lagu soo saaraa isku-darka kiimikaad, oo ka madax bannaan borotiinnada unugyada martida loo yahay iyo hadhaaga DNA, iyadoo la hubinayo badbaadada noole ee wanaagsan iyo tayada joogtada ah. U hoggaansanaanta tilmaamaha FDA, badeecadayadu waxay la kulantaa xaddidaadyo wasakhnimo adag waxayna taageertaa wax soo saarka ballaaran.
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Retatrutide
Retaglutide waa dipeptidyl peptidase-4 (DPP-4) cusub inhibitor fasalka hypoglycemic daroogada taas oo ka hortagi karta hoos u dhaca glucagon-sida peptide-1 (GLP-1) iyo gulukooska-ku-tiirsan insulin-sii daayo polypeptide (GIP) by DPP-4 enzyme ee xiidmaha iyo dhiigga, sii dheeraynaysaa unugyada pancreatic insulin. heerka aasaasiga ah ee insulin soonka, iyada oo la yareynayo dheecaanka glucagon ee unugyada α-pancreatic, si wax ku ool ah loo xakameeyo sonkorta dhiigga ka dib. Waxay si fiican u shaqeysaa marka la eego saameynta hypoglycemic, dulqaadka, iyo u hoggaansanaanta.
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Liraglutide Anti-Diabetics ee Xakamaynta Sonkorta Dhiiga CAS NO.204656-20-2
Walaxda firfircoon:Liraglutide (analog of glucagon-like peptide-1 (GLP-1) oo ay soo saartay khamiir iyada oo loo marayo tignoolajiyada dib-u-habaynta hidda-socodka).
Magaca Kiimikada:Arg34Lys26-(N-ε-(γ-Glu(N-α-hexadecanoyl)))-GLP-1[7-37]
Waxyaabaha kale:Disodium Hydrogen Fosfate Dihydrate, Propylene Glycol, Hydrochloric Acid iyo/ama Sodium Hydroxide (sida hagaajinta pH Keliya), Phenol, iyo Biyaha la isku duro.
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Leuprorelin Acetate waxay xakameysaa dheecaanka hormoonnada Gonadal
Magaca: Leuprorelin
Lambarka CAS: 53714-56-0
Qaaciddada molecular: C59H84N16O12
Miisaanka molecular: 1209.4
Lambarka EINECS: 633-395-9
Wareeg gaar ah: D25 -31.7° (c = 1 1% acetic acid)
Cufnaanta: 1.44± 0.1 g/cm3 (La saadaaliyay)
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BPC-157
BPC-157 API waxay qabataa habka isku-dhafka wajiga adag (SPPS):
Nadiifin sare: ≥99% (HPLC ogaanshaha)
Hadhaaga wasakhda hoose, ma laha endotoxin, ma laha wasakhowga birta culus
Xasilooni Dufcaddii, ku celin xoog leh, isticmaalka heerka duritaanka taageerada
Taageero sahayda garaam iyo kiiloogaraam si loo daboolo baahiyaha heerarka kala duwan ee R&D ilaa warshadaynta. -
CJC-1295
CJC-1295 API waxaa la soo saaray iyadoo la adeegsanayo tignoolajiyada adag ee peptide synthesis (SPPS) waxaana lagu nadiifiyaa iyadoo la isticmaalayo HPLC si loo gaaro nadiifnimo sare iyo joogteynta Dufcaddii-ilaa- Dufcaddii.
Astaamaha Alaabta:daahirnimo ≥ 99%
Walxaha haraaga ah ee hooseeya iyo biraha culus
Endotoxin-free, waddada isku-dhafka aan difaaca jirka ahayn
Tirada la beddeli karo: mg ilaa kg
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NAD+
Tilmaamaha API:
Nadiifin sare ≥99%
NAD+-dawada
Heerarka wax soo saarka ee GMP
NAD+ API waxay ku habboon tahay in loo isticmaalo nafaqooyinka, cirbadaha, iyo daawaynta dheef-shiid kiimikaad sare leh.
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Cagrilintide
Cagrilintide waa synthetic, amylin reseptor agonist oo muddo dheer shaqaynaysa oo loo sameeyay daaweynta buurnaanta iyo xanuunnada dheef-shiid kiimikaadka la xiriira. Iyagoo ku dayanaya hormoonka dabiiciga ah ee amylin, waxay ka caawisaa nidaaminta rabitaanka cuntada, hoos u dhigista faaruqinta caloosha, iyo kor u qaadida dheregnaanta. Cagrilintide API ee nadiifka ah ee nadiifka ah waxaa lagu soo saaraa isku-darka kiimikaad waxayna la kulantaa heerarka-farmasiga, taasoo ka dhigaysa mid ku habboon in loo isticmaalo hababka maaraynta miisaanka horumarsan.
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Tesamorelin
Tesamorelin API waxay isticmaashaa tignoolajiyada horumarsan ee adag ee peptide synthesis (SPPS) waxayna leedahay sifooyinka soo socda:
Nadiifinta ≥99% (HPLC)
Ma jiro endotoxin, biraha culus, dareerayaasha haraaga ah ee la tijaabiyay
Amino acid isku xigxiga iyo qaab dhismeedka uu xaqiijiyay LC-MS/NMR
Bixi wax soo saar la habeeyey oo garaam ilaa kiilo garaam -
N-Acetylneuraminik Acid (Neu5Ac Sialic Acid)
N-Acetylneuraminic Acid (Neu5Ac), oo loo yaqaan sialic acid, waa monosaccharide si dabiici ah u dhaca oo ku lug leh hawlaha unugyada iyo difaaca jirka. Waxay door muhiim ah ka ciyaartaa calaamadaynta unugyada, difaaca pathogene, iyo horumarinta maskaxda.
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Ergothionine
Ergothioneine waa antioxidant dabiici ah oo ka soo jeeda amino acid, oo lagu bartay sifooyinkeeda cytoprotective iyo ka hortagga gabowga. Waxa lagu farsameeyaa fungi iyo bakteeriya waxayna ku ururtaa unugyo soo gaadhay cadaadis oksaydh ah.