Hexarelin

Hexarelin API - Dulmarka alaabta

Hexarelinwaa synthetichormoonka koritaanka ee secretagogue peptide (GHS)oo awood lehGHSR-1a agonist, loo sameeyay kicintasoo daynta hormoonka koritaanka endogenous (GH).. Waxaa iska lehqoyska ghrelin mimeticwaxayna ka kooban tahay lix amino acids (hexapeptide), oo bixiya xasiloonida dheef-shiid kiimikaadka iyo saamaynta sii daynta GH oo xoogan marka loo eego analoogyadii hore sida GHRP-6.

Hexarelin waxaa si weyn loogu bartay codsiyadeeda gudahaendocrinology, luminta murqaha, hagaajinta wadnaha, iyo daawaynta ka hortagga gabowga, iyada oo ay ugu wacan tahay awoodda ay si dabiici ah kor ugu qaaddo GH iyofactor koritaanka insulin-sida 1 (IGF-1)heerarka iyada oo aan si toos ah loo soo bandhigin hormoonnada dibadda.

Habka Waxqabadka

Hexarelin waxay ku xidhan tahaySoo-dhoweeyaha hormoonka korriinka ee qarsoodiga ah (GHSR-1a)on pituitary iyo hypothalamus, ekaanaysa ficilkaghrelin-gajada dabiiciga ah ee jidhka iyo hormoonka GH-soo daaya.

Ficilada nafsiga ah ee muhiimka ah:

• Waxay kicisaa sii daynta garaaca wadnaha ee GH

• Waxay kordhisaa wareeggaIGF-1heerarka

• Kor u qaadasaamaynta anabolic(koritaanka murqaha, soo kabashada)

• Taageerodheef-shiid kiimikaadiyodib u soo kabashada unugyada

• Waxaa laga yaabaa inuu soo bandhigoilaalinta wadnahaiyoanti-apoptoticsaamayn

Si ka duwan qaar ka mid ah GHS peptides, Hexarelin ayaa sameeyasi weyn uma kordhin cortisol ama prolactin, oo bixiya profile-ka endocrine oo nadiif ah.

Cilmi-baarista iyo Daawaynta ee suurtogalka ah

1. Kobaca Murqaha & Soo kabashada

• Kor u qaadacufnaanta jirka oo caato ahhorumarinta

• Kobcintahagaajinta murqaha iyo dib u soo kabashada

• Wax ku bartaysarcopenia, cachexia, iyo soo kabashada qalliinka kadib

2. Ilaalinta Wadnaha

• Daraasado hore ayaa muujinayashaqada wadnaha oo hagaagtaydhaawaca myocardial ka dib

• Wax yareeyafibrosis wadnahaoo wanaajiyajajab ka saarista hawo-mareenka bidix

• Isticmaalka suurtagalka ah ee gudahawadne xanuuniyogabowga wadnahamoodooyinka

3. Dheef-shiid kiimikaad iyo ka-hortagga gabowga

• Kordheysalipolysisoo horumarisadareenka insulin

• Taageerodaawaynta ka hortagga gabowgaiyada oo loo marayo GH/IGF-1 kicinta dhidibka

• Waxaa laga yaabaa inay ku caawiso ilaalintacufnaanta lafaha iyo caafimaadka xubnaha

Tilmaamaha API (Kooxda Gentolex)

• daahirnimo ≥ 99%

• Soo saaray viaWajiga adag ee peptide synthesis (SPPS)

• Heerarka GMP-sida, endotoxin hooseeya iyo haraaga dareeraha

• Sahayda dabacsan:R&D ilaa miisaanka ganacsiga