AEEA-AAEEA

AEEA-AEEA (Aminoethoxyethoxyacetate dimer)

Codsiga Cilmi-baarista:
AEEA-AEEA waa hydrophilic, spacer dabacsan oo caadi ahaan loo isticmaalo peptide iyo cilmi-baarista isku xirka daroogada. Waxay ka kooban tahay laba qaybood oo ah ethylene glycol, taas oo ka dhigaysa mid faa'iido u leh barashada saameynta dhererka iskuxiraha iyo dabacsanaanta isdhexgalka molecular, solubility, iyo dhaqdhaqaaqa noolaha. Cilmi-baadhayaashu waxay inta badan isticmaalaan cutubyada AEEA si ay u qiimeeyaan sida spacers u saameeyaan waxqabadka isku-xidhayaasha daawada-antibody-ga (ADCs), conjugates-peptide-daroogada, iyo bioconjugates kale.

Shaqada:
AEEA-AEEA waxay u shaqeysaa sidii iskuxiraha noole la jaan qaadi kara oo xoojisa milanka, yareeya caqabada adag, oo wanaajisa dabacsanaanta molecular. Waxay ka caawisaa kala soocida xayndaabyada shaqaynaya ee molecule, sida beegsiga ligands iyo culaysyada mushaharka, taas oo u oggolaanaysa xidhid iyo hawlo hufan. Dabeecaddeeda aan difaaca jirka ahayn iyo hydrophilic sidoo kale waxay gacan ka geysataa hagaajinta profiles farmashiyaha ee codsiyada daweynta.